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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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CT83
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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

CT83

Gene description

Cancer/testis antigen 83

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (HeLa, U-266/70, U-266/84)
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

RNA-based expert annotation gave inconclusive results. Antibody staining not consistent with RNA expression data.

Reliability score

Uncertain based on 1 antibody.
HPA004773
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA004773

Cancer

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Cancer

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

A majority of malignant cells displayed moderate cytoplasmic staining with a granular pattern. Strong positivity was observed in most colorectal cancers and malignant melanomas.

GENE INFORMATION

Gene name

CT83 (HGNC Symbol)

Synonyms

CXorf61, FLJ20611, FLJ22913, KK-LC-1

Description

Cancer/testis antigen 83 (HGNC Symbol)

Entrez gene summary

Chromosome

X

Cytoband

q23

Chromosome location (bp)

116461682 - 116463003

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204019 (version 83.38)

Entrez gene

203413

UniProt

Q5H943 (UniProt - Evidence at protein level)

neXtProt

NX_Q5H943

Antibodypedia

CT83 antibodies

PROTEIN BROWSER

CT83-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CT83-001
ENSP00000360961
ENST00000371894
Q5H943 [Direct mapping]
Kita-kyushu lung cancer antigen 1
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005634 [nucleus]
GO:0005886 [plasma membrane]
GO:0016021 [integral component of membrane]
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113 aa
12.8 kDa
No 0

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