Expression of TCEAL6 in cancer - Summary - The Human Protein Atlas

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TCEAL6

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TCEAL6
Gene description	Transcription elongation factor A (SII)-like 6
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (glioma)
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (adrenal gland, cerebral cortex, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression mainly in cells in seminiferous ducts.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA045564 , HPA058982
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA045564	HPA058982

GENE INFORMATION
Gene name	TCEAL6 (HGNC Symbol)
Synonyms	WEX2
Description	Transcription elongation factor A (SII)-like 6 (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	q22.1
Chromosome location (bp)	102140476 - 102142970
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204071 (version 83.38)
Entrez gene	158931
UniProt	Q6IPX3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6IPX3
Antibodypedia	TCEAL6 antibodies

PROTEIN BROWSER

TCEAL6-001	TCEAL6-002	TCEAL6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TCEAL6-001 ENSP00000361860 ENST00000372774	Q6IPX3 [Direct mapping] Transcription elongation factor A protein-like 6 A0A024RCH0 [Target identity:100%; Query identity:100%] Transcription elongation factor A (SII)-like 6, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0050699 [WW domain binding] Show all	183 aa 20.3 kDa	No	0
TCEAL6-002 ENSP00000361859 ENST00000372773	Q6IPX3 [Direct mapping] Transcription elongation factor A protein-like 6 A0A024RCH0 [Target identity:100%; Query identity:100%] Transcription elongation factor A (SII)-like 6, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0050699 [WW domain binding] Show all	183 aa 20.3 kDa	No	0
TCEAL6-201 ENSP00000482574 ENST00000622517	A0A087WZD5 [Direct mapping] Transcription elongation factor A protein-like 6 Show all	Predicted intracellular proteins Show all		199 aa 22.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.