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All cancer cells showed weak to moderate cytoplasmic staining. Gliomas and lymphomas were virtually negative.
GENE INFORMATION
Gene name
INPP5B
Synonyms
Description
Inositol polyphosphate-5-phosphatase B (HGNC Symbol)
Entrez gene summary
This gene encodes a member of a family of inositol polyphosphate-5-phosphatases. These enzymes function in the regulation of calcium signaling by inactivating inositol phosphates. The encoded protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jul 2014]
P32019 [Direct mapping] Type II inositol 1,4,5-trisphosphate 5-phosphatase
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Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)