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Several malignant gliomas, skin, testicular, cervical and breast cancers displayed moderate nuclear and/or cytoplasmic immunoreactivity. Malignant cells in general were weakly stained or negative.
GENE INFORMATION
Gene name
MAFB (HGNC Symbol)
Synonyms
KRML
Description
V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns. [provided by RefSeq, Jul 2008]