Expression of AGAP9 in cancer - Summary - The Human Protein Atlas

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AGAP9

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	AGAP9
Gene description	ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA042490
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), colorectal cancer (unfavourable) and urothelial cancer (favourable).
Renal cancer p<0.001 Colorectal cancer p<0.001 Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042490

GENE INFORMATION
Gene name	AGAP9 (HGNC Symbol)
Synonyms	bA301J7.2, CTGLF6, FLJ00312
Description	ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q11.22
Chromosome location (bp)	47501854 - 47523638
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000204172 (version 83.38)
Entrez gene	642517
UniProt	Q5VTM2 (UniProt - Inferred from homology)
neXtProt	NX_Q5VTM2
Antibodypedia	AGAP9 antibodies

PROTEIN BROWSER

AGAP9-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AGAP9-001 ENSP00000392206 ENST00000452145	Q5VTM2 [Direct mapping] Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9 Show all	Predicted intracellular proteins Show all	GO:0005096 [GTPase activator activity] GO:0043547 [positive regulation of GTPase activity] GO:0046872 [metal ion binding] Show all	658 aa 72.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.