Expression of GPRIN2 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

GPRIN2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GPRIN2
Gene description	G protein regulated inducer of neurite outgrowth 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Group enriched (A-431, A549, SiHa, SK-BR-3)
HPA (normal tissue):	Tissue enhanced (lung, skin)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression in most tissues, including skin and cerebellum.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. GTEx data supports antibody staining in cerebellum.
Reliability score	Approved based on 1 antibody. HPA038129
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (unfavourable) and head and neck cancer (favourable).
Endometrial cancer p<0.001 Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038129

GENE INFORMATION
Gene name	GPRIN2 (HGNC Symbol)
Synonyms	KIAA0514, MGC15171
Description	G protein regulated inducer of neurite outgrowth 2 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q11.22
Chromosome location (bp)	46549044 - 46555530
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204175 (version 83.38)
Entrez gene	9721
UniProt	O60269 (UniProt - Evidence at protein level)
neXtProt	NX_O60269
Antibodypedia	GPRIN2 antibodies

PROTEIN BROWSER

GPRIN2-001	GPRIN2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPRIN2-001 ENSP00000363436 ENST00000374317	O60269 [Direct mapping] G protein-regulated inducer of neurite outgrowth 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	458 aa 47.5 kDa	No	0
GPRIN2-201 ENSP00000363433 ENST00000374314	O60269 [Direct mapping] G protein-regulated inducer of neurite outgrowth 2 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	458 aa 47.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.