Cell atlas - XAGE1B - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

XAGE1B

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear speckles

Human cell
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	XAGE1B
Gene description	X antigen family, member 1B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nuclear speckles. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Cell line enhanced (U-266/84, HMC-1, U-2 OS, THP-1, NB-4, U-937)
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear speckles (uncertain)

DATA RELIABILITY
Reliability score	Uncertain based on 1 antibody. HPA077164
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-266/84, HMC-1, U-2 OS, THP-1, NB-4, U-937) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nuclear speckles. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nuclear speckles (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA077164	A549	Nuclear speckles
	HPA077164	U-2 OS	Nuclear speckles
	HPA077164	U-251 MG	Nuclear speckles

GENE INFORMATION
Gene name	XAGE1B (HGNC Symbol)
Synonyms	CT12.1b
Description	X antigen family, member 1B (HGNC Symbol)
Entrez gene summary	This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Chromosome	X
Cytoband	p11.22
Chromosome location (bp)	52512077 - 52520803
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204382 (version 83.38)
Entrez gene	653220
UniProt	Q9HD64 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HD64
Antibodypedia	XAGE1B antibodies

PROTEIN BROWSER

XAGE1B-001	XAGE1B-003	XAGE1B-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
XAGE1B-001 ENSP00000364766 ENST00000375616	Q9HD64 [Direct mapping] X antigen family member 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	81 aa 9.1 kDa	No	0
XAGE1B-003 ENSP00000364763 ENST00000375613	Q9HD64 [Direct mapping] X antigen family member 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	69 aa 8 kDa	No	0
XAGE1B-006 ENSP00000430130 ENST00000518075	Q9HD64 [Direct mapping] X antigen family member 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	81 aa 9.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.