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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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ZNF814
  • TISSUE

  • CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

ZNF814

Gene description

Zinc finger protein 814

Protein class

Cancer-related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

9
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Mixed
HPA (cell line):Expressed in all
HPA (normal tissue):Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.

Reliability score

Approved based on 2 antibodies.
HPA043800 , HPA053762
SHOW MORE

PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA043800
HPA053762

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Adenocarcinoma of head & neck showed strong cytoplasmic immunoreactivity. Cases of melanomas, endometrial and pancreatic cancers were moderately stained. Remaining cancers were in general negative.

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Cases of colorectal, prostate, skin, urothelial, stomach and liver cancers showed moderate to strong cytoplasmic and/or nuclear staining. Remaining tumor cells were negative.

GENE INFORMATION

Gene name

ZNF814

Synonyms

Description

Zinc finger protein 814 (HGNC Symbol)

Entrez gene summary

Chromosome

19

Cytoband

q13.43

Chromosome location (bp)

57848731 - 57889074

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204514 (version 83.38)

Entrez gene

730051

UniProt

B7Z6K7 (UniProt - Evidence at protein level)

neXtProt

NX_B7Z6K7

Antibodypedia

ZNF814 antibodies

PROTEIN BROWSER

ZNF814-001
ZNF814-002
ZNF814-003
ZNF814-006
ZNF814-008
ZNF814-010
ZNF814-012
ZNF814-014
ZNF814-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZNF814-001
ENSP00000410545
ENST00000435989
B7Z6K7 [Direct mapping]
Putative uncharacterized zinc finger protein 814
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Cancer-related genes
   Mutational cancer driver genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
855 aa
97.3 kDa
No 0
ZNF814-002
ENSP00000470296
ENST00000597342
M0QZ45 [Direct mapping]
Putative uncharacterized zinc finger protein 814
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
113 aa
12.3 kDa
No 0
ZNF814-003
ENSP00000469641
ENST00000597807
M0QY74 [Direct mapping]
Putative uncharacterized zinc finger protein 814
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
62 aa
6.9 kDa
No 0
ZNF814-006
ENSP00000472089
ENST00000600634
M0R0R0 [Direct mapping]
Putative uncharacterized zinc finger protein 814
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
91 aa
9.8 kDa
No 0
ZNF814-008
ENSP00000469704
ENST00000595295
M0QYA7 [Direct mapping]
Putative uncharacterized zinc finger protein 814
Show all
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
39 aa
4.2 kDa
No 0
ZNF814-010
ENSP00000469912
ENST00000597832
M0QYL6 [Direct mapping]
Putative uncharacterized zinc finger protein 814
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
68 aa
7.6 kDa
No 0
ZNF814-012
ENSP00000470748
ENST00000595048
M0QZS8 [Direct mapping]
Putative uncharacterized zinc finger protein 814
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
94 aa
10.3 kDa
No 0
ZNF814-014
ENSP00000470328
ENST00000596604
M0QZ64 [Direct mapping]
Putative uncharacterized zinc finger protein 814
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
84 aa
9.1 kDa
No 0
ZNF814-201
ENSP00000480123
ENST00000614383
A0A087WWD1 [Direct mapping]
Putative uncharacterized zinc finger protein 814
Show all
Predicted intracellular proteins
Cancer-related genes
   Mutational cancer driver genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
577 aa
65.5 kDa
No 0

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