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Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

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Method

Validation

Method

Validation

Method

Validation

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Searches

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Cancer

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Tissue

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Antibodies

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AADACL4
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

AADACL4

Gene description

Arylacetamide deacetylase-like 4

Protein class

Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Not detected

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification.

Reliability score

Uncertain based on 1 antibody.
HPA043588
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA043588

Cancer

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Cancer

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Moderate to strong cytoplasmic immunoreactivity, often with a granular pattern was observed in most cancer tissues. Malignant carcinoids, non-Hodgkin's lymphomas along with several lung and renal cancers were weakly stained or negative.

GENE INFORMATION

Gene name

AADACL4

Synonyms

Description

Arylacetamide deacetylase-like 4 (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

p36.21

Chromosome location (bp)

12644547 - 12667086

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204518 (version 83.38)

Entrez gene

343066

UniProt

Q5VUY2 (UniProt - Inferred from homology)

neXtProt

NX_Q5VUY2

Antibodypedia

AADACL4 antibodies

PROTEIN BROWSER

AADACL4-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AADACL4-001
ENSP00000365395
ENST00000376221
Q5VUY2 [Direct mapping]
Arylacetamide deacetylase-like 4
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016787 [hydrolase activity]
GO:0052689 [carboxylic ester hydrolase activity]
Show all
407 aa
46.1 kDa
No 1

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