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MUC21

GENERAL INFORMATION

Gene name

 MUC21

Gene description

 Mucin 21, cell surface associated

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (esophagus)
GTEx:Tissue enhanced (esophagus, vagina)
FANTOM5:Tissue enhanced (esophagus, tonsil)

Protein evidence

 Evidence at protein level

Protein expression

 Membranous expression in squamous epithelia of esophagus, vagina and cervix.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. External characterization data supports antibody staining.

Reliability score

 Supported based on 1 antibody.
HPA052028
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Esophagus

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (esophagus)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (esophagus, vagina)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (esophagus, tonsil)

GENE INFORMATION

Gene name

 MUC21 (HGNC Symbol)

Synonyms

 bCX31G15.2, C6orf205

Description

 Mucin 21, cell surface associated (HGNC Symbol)

Entrez gene summary

Chromosome

 6

Cytoband

 p21.33

Chromosome location (bp)

 30983718 - 30989903

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000204544 (version 83.38)

Entrez gene

 394263

UniProt

 Q5SSG8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5SSG8

Antibodypedia

 MUC21 antibodies

PROTEIN BROWSER
MUC21-001
MUC21-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MUC21-001
ENSP00000365473
ENST00000376296
Q5SSG8 [Direct mapping]
Mucin-21
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
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GO:0005796 [Golgi lumen]
GO:0005886 [plasma membrane]
GO:0006493 [protein O-linked glycosylation]
GO:0010812 [negative regulation of cell-substrate adhesion]
GO:0016021 [integral component of membrane]
GO:0016266 [O-glycan processing]
GO:0022408 [negative regulation of cell-cell adhesion]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0070062 [extracellular exosome]
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 566 aa
54.2 kDa 		Yes 1
MUC21-002
ENSP00000457640
ENST00000486149
A0A0C4DGM6 [Direct mapping]
Mucin-21
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
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GO:0016021 [integral component of membrane]
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 112 aa
12 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.