Expression of MAS1L in cancer - Summary - The Human Protein Atlas

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MAS1L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MAS1L
Gene description	MAS1 proto-oncogene like, G protein-coupled receptor
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enhanced (cervix, uterine)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA017983
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA017983

GENE INFORMATION
Gene name	MAS1L (HGNC Symbol)
Synonyms	dJ994E9.2, MAS-L, MRG
Description	MAS1 proto-oncogene like, G protein-coupled receptor (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p22.1
Chromosome location (bp)	29486697 - 29487956
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000204687 (version 83.38)
Entrez gene	116511
UniProt	P35410 (UniProt - Evidence at transcript level)
neXtProt	NX_P35410
Antibodypedia	MAS1L antibodies

PROTEIN BROWSER

MAS1L-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MAS1L-001 ENSP00000366331 ENST00000377127	P35410 [Direct mapping] Mas-related G-protein coupled receptor MRG W8W3J1 [Target identity:100%; Query identity:100%] Mas-related G protein-coupled receptor H Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	378 aa 42.4 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.