Expression of FAM221B in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

FAM221B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM221B
Gene description	Family with sequence similarity 221, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (bone marrow, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 2 antibodies. HPA023011 , HPA026577
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Urothelial cancer

STAINING SUMMARY

HPA023011	HPA026577

GENE INFORMATION
Gene name	FAM221B (HGNC Symbol)
Synonyms	C9orf128
Description	Family with sequence similarity 221, member B (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p13.3
Chromosome location (bp)	35816391 - 35828747
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000204930 (version 83.38)
Entrez gene	392307
UniProt	A6H8Z2 (UniProt - Evidence at transcript level)
neXtProt	NX_A6H8Z2
Antibodypedia	FAM221B antibodies

PROTEIN BROWSER

FAM221B-002	FAM221B-003	FAM221B-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM221B-002 ENSP00000415299 ENST00000423537	A6H8Z2 [Direct mapping] Protein FAM221B Show all	Predicted intracellular proteins Show all		402 aa 45.4 kDa	No	0
FAM221B-003 ENSP00000367222 ENST00000377984	F8W8N9 [Direct mapping] Protein FAM221B Show all	Predicted intracellular proteins Show all		301 aa 33.5 kDa	No	0
FAM221B-004 ENSP00000420279 ENST00000472182	C9JPK8 [Direct mapping] Protein FAM221B Show all	Predicted intracellular proteins Show all		90 aa 10 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.