Expression of LRRC10B in cancer - Summary - The Human Protein Atlas

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LRRC10B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	LRRC10B
Gene description	Leucine rich repeat containing 10B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Group enriched (AF22, RH-30, SCLC-21H)
HPA (normal tissue):	Tissue enriched (fallopian tube)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA047619
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA047619

GENE INFORMATION
Gene name	LRRC10B
Synonyms
Description	Leucine rich repeat containing 10B (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q12.2
Chromosome location (bp)	61508800 - 61511018
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204950 (version 83.38)
Entrez gene	390205
UniProt	A6NIK2 (UniProt - Predicted)
neXtProt	NX_A6NIK2
Antibodypedia	LRRC10B antibodies

PROTEIN BROWSER

LRRC10B-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRRC10B-001 ENSP00000367315 ENST00000378075	A6NIK2 [Direct mapping] Leucine-rich repeat-containing protein 10B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	292 aa 32.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.