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SARNP

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GENERAL INFORMATION

Gene name

 SARNP

Gene description

 SAP domain containing ribonucleoprotein

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the nuclear speckles. Caution: Based on antibodies targeting proteins from multiple genes.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nuclear speckles (supported)

DATA RELIABILITY

Reliability score

 Supported based on 2 antibodies.
HPA030902 , HPA030903
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the nuclear speckles. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

 Nuclear speckles (supported)

 

 

 
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Low
High
G1
S
G2
M
N/A

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Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA030902 A-431 Nuclear speckles
HPA030902 U-2 OS Nuclear speckles
HPA030902 U-251 MG Nuclear speckles
HPA030903 A-431 Nuclear speckles
HPA030903 U-2 OS Nuclear speckles
Cytoplasmic bodies
HPA030903 U-251 MG Nuclear speckles
Cytoplasmic bodies

GENE INFORMATION

Gene name

 SARNP (HGNC Symbol)

Synonyms

 CIP29, Hcc-1, THO1

Description

 SAP domain containing ribonucleoprotein (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]

Chromosome

 12

Cytoband

 q13.2

Chromosome location (bp)

 55752463 - 55817756

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000205323 (version 83.38)

Entrez gene

 84324

UniProt

 P82979 (UniProt - Evidence at protein level)

neXtProt

 NX_P82979

Antibodypedia

 SARNP antibodies

PROTEIN BROWSER
SARNP-002
SARNP-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SARNP-002
ENSP00000337632
ENST00000336133
P82979 [Direct mapping]
SAP domain-containing ribonucleoprotein
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000346 [transcription export complex]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006406 [mRNA export from nucleus]
GO:0006417 [regulation of translation]
GO:0016607 [nuclear speck]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0044822 [poly(A) RNA binding]
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 210 aa
23.7 kDa 		No 0
SARNP-005
ENSP00000447690
ENST00000552080
F8VZQ9 [Direct mapping]
SAP domain-containing ribonucleoprotein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
 213 aa
24.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.