Expression of MT1H in cancer - Summary - The Human Protein Atlas

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MT1H

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	MT1H
Gene description	Metallothionein 1H
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (testis cancer)
HPA (cell line):	Cell line enhanced (BEWO, EFO-21, SCLC-21H)
HPA (normal tissue):	Tissue enhanced (kidney, small intestine, thyroid gland)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in glioma (unfavourable) and renal cancer (unfavourable).
Glioma p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (testis cancer)

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	MT1H (HGNC Symbol)
Synonyms	MT1
Description	Metallothionein 1H (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q13
Chromosome location (bp)	56669814 - 56671129
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000205358 (version 83.38)
Entrez gene	4496
UniProt	P80294 (UniProt - Evidence at protein level)
neXtProt	NX_P80294
Antibodypedia	MT1H antibodies

PROTEIN BROWSER

MT1H-001	MT1H-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MT1H-001 ENSP00000330587 ENST00000332374	P80294 [Direct mapping] Metallothionein-1H Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0008270 [zinc ion binding] GO:0045926 [negative regulation of growth] GO:0046872 [metal ion binding] GO:0048471 [perinuclear region of cytoplasm] GO:0071276 [cellular response to cadmium ion] GO:0071294 [cellular response to zinc ion] Show all	61 aa 6 kDa	No	0
MT1H-002 ENSP00000457114 ENST00000569155	H3BTC4 [Direct mapping] Metallothionein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	85 aa 8.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.