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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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SLCO6A1
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    TISSUE

  • CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

SLCO6A1

Gene description

Solute carrier organic anion transporter family, member 6A1

Protein class

Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Distinct membranous expression in seminiferous ducts.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 1 antibody.
HPA054126
SHOW MORE

PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA054126

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Essentially all cancer tissues were negative.

GENE INFORMATION

Gene name

SLCO6A1 (HGNC Symbol)

Synonyms

CT48, MGC26949, OATP6A1, OATPY

Description

Solute carrier organic anion transporter family, member 6A1 (HGNC Symbol)

Entrez gene summary

Chromosome

5

Cytoband

q21.1

Chromosome location (bp)

102371782 - 102499016

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000205359 (version 83.38)

Entrez gene

133482

UniProt

Q86UG4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q86UG4

Antibodypedia

SLCO6A1 antibodies

PROTEIN BROWSER

SLCO6A1-001
SLCO6A1-002
SLCO6A1-003
SLCO6A1-004
SLCO6A1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLCO6A1-001
ENSP00000421339
ENST00000506729
Q86UG4 [Direct mapping]
Solute carrier organic anion transporter family member 6A1
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Show all
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0005887 [integral component of plasma membrane]
GO:0006810 [transport]
GO:0015347 [sodium-independent organic anion transmembrane transporter activity]
GO:0016020 [membrane]
GO:0043252 [sodium-independent organic anion transport]
GO:0098656 [anion transmembrane transport]
Show all
719 aa
79.2 kDa
No >9
SLCO6A1-002
ENSP00000369135
ENST00000379807
Q86UG4 [Direct mapping]
Solute carrier organic anion transporter family member 6A1
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Show all
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0005887 [integral component of plasma membrane]
GO:0006810 [transport]
GO:0015347 [sodium-independent organic anion transmembrane transporter activity]
GO:0016020 [membrane]
GO:0043252 [sodium-independent organic anion transport]
GO:0098656 [anion transmembrane transport]
Show all
719 aa
79.2 kDa
No >9
SLCO6A1-003
ENSP00000373671
ENST00000389019
Q86UG4 [Direct mapping]
Solute carrier organic anion transporter family member 6A1
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Show all
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0005887 [integral component of plasma membrane]
GO:0006810 [transport]
GO:0015347 [sodium-independent organic anion transmembrane transporter activity]
GO:0016020 [membrane]
GO:0043252 [sodium-independent organic anion transport]
GO:0098656 [anion transmembrane transport]
Show all
657 aa
72.6 kDa
No >9
SLCO6A1-004
ENSP00000421990
ENST00000513675
C9J020 [Direct mapping]
Solute carrier organic anion transporter family member 6A1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0006810 [transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
466 aa
51.4 kDa
No 7
SLCO6A1-005
ENSP00000421846
ENST00000511588
H0Y8R6 [Direct mapping]
Solute carrier organic anion transporter family member 6A1
Show all
Predicted intracellular proteins
Show all
25 aa
2.9 kDa
No 0

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