Expression of EXOC3L4 in cancer - Summary - The Human Protein Atlas

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EXOC3L4

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	EXOC3L4
Gene description	Exocyst complex component 3-like 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (liver cancer)
HPA (cell line):	Cell line enhanced (HDLM-2, HEL, Hep G2, RPMI-8226)
HPA (normal tissue):	Tissue enhanced (duodenum)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA043661
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PROGNOSTIC SUMMARY
Prognostic marker in colorectal cancer (unfavourable).
Colorectal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (liver cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Pancreatic cancer

STAINING SUMMARY

HPA043661

GENE INFORMATION
Gene name	EXOC3L4 (HGNC Symbol)
Synonyms	C14orf73
Description	Exocyst complex component 3-like 4 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q32.32
Chromosome location (bp)	103100144 - 103110559
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000205436 (version 83.38)
Entrez gene	91828
UniProt	Q17RC7 (UniProt - Evidence at protein level)
neXtProt	NX_Q17RC7
Antibodypedia	EXOC3L4 antibodies

PROTEIN BROWSER

EXOC3L4-001	EXOC3L4-005	EXOC3L4-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EXOC3L4-001 ENSP00000369409 ENST00000380069	Q17RC7 [Direct mapping] Exocyst complex component 3-like protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000145 [exocyst] GO:0000149 [SNARE binding] GO:0006887 [exocytosis] GO:0051601 [exocyst localization] Show all	722 aa 79.9 kDa	No	0
EXOC3L4-005 ENSP00000454163 ENST00000559116	H0YNV0 [Direct mapping] Exocyst complex component 3-like protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000145 [exocyst] GO:0000149 [SNARE binding] GO:0006887 [exocytosis] GO:0051601 [exocyst localization] Show all	153 aa 16.7 kDa	No	0
EXOC3L4-007 ENSP00000454036 ENST00000560304	H0YNJ4 [Direct mapping] Exocyst complex component 3-like protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000145 [exocyst] GO:0000149 [SNARE binding] GO:0006887 [exocytosis] GO:0051601 [exocyst localization] Show all	212 aa 23.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.