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ACOT6

GENERAL INFORMATION

Gene name

 ACOT6

Gene description

 Acyl-CoA thioesterase 6

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Cell line enriched (T-47d)
HPA (normal tissue):Tissue enhanced (kidney)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA058258
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA058258

GENE INFORMATION

Gene name

 ACOT6 (HGNC Symbol)

Synonyms

 C14orf42

Description

 Acyl-CoA thioesterase 6 (HGNC Symbol)

Entrez gene summary

Chromosome

 14

Cytoband

 q24.3

Chromosome location (bp)

 73610945 - 73619888

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000205669 (version 83.38)

Entrez gene

 641372

UniProt

 Q3I5F7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q3I5F7

Antibodypedia

 ACOT6 antibodies

PROTEIN BROWSER
ACOT6-001
ACOT6-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ACOT6-001
ENSP00000370531
ENST00000381139
Q3I5F7 [Direct mapping]
Putative acyl-coenzyme A thioesterase 6
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   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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GO:0005782 [peroxisomal matrix]
GO:0005829 [cytosol]
GO:0019432 [triglyceride biosynthetic process]
GO:0035338 [long-chain fatty-acyl-CoA biosynthetic process]
GO:0044255 [cellular lipid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0052689 [carboxylic ester hydrolase activity]
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 207 aa
23 kDa 		No 0
ACOT6-002
ENSP00000451464
ENST00000554229
G3V3W6 [Direct mapping]
Putative acyl-coenzyme A thioesterase 6
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   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
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 168 aa
18.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.