Expression of C17orf107 in cancer - Summary - The Human Protein Atlas

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C17orf107

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C17orf107
Gene description	Chromosome 17 open reading frame 107
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HMC-1, hTCEpi)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA069713
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PROGNOSTIC SUMMARY
Prognostic marker in breast cancer (favourable), renal cancer (favourable) and pancreatic cancer (favourable).
Breast cancer p<0.001 Renal cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA069713

GENE INFORMATION
Gene name	C17orf107
Synonyms
Description	Chromosome 17 open reading frame 107 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.2
Chromosome location (bp)	4899418 - 4902932
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000205710 (version 83.38)
Entrez gene	100130311
UniProt	Q6ZR85 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6ZR85
Antibodypedia	C17orf107 antibodies

PROTEIN BROWSER

C17orf107-001	C17orf107-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C17orf107-001 ENSP00000370770 ENST00000381365	Q6ZR85 [Direct mapping] Uncharacterized protein C17orf107 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		190 aa 19.9 kDa	No	0
C17orf107-002 ENSP00000429241 ENST00000521575	E5RJ01 [Direct mapping] Uncharacterized protein C17orf107 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all		98 aa 10.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.