Expression of STK38L in cancer - Summary - The Human Protein Atlas

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STK38L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	STK38L
Gene description	Serine/threonine kinase 38 like
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and membrane expression in several different tissue types.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene.
Reliability score	Approved based on 1 antibody. HPA038623
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (unfavourable).
Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038623

GENE INFORMATION
Gene name	STK38L (HGNC Symbol)
Synonyms	KIAA0965, NDR2
Description	Serine/threonine kinase 38 like (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	p11.23
Chromosome location (bp)	27243968 - 27325959
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000211455 (version 83.38)
Entrez gene	23012
UniProt	Q9Y2H1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2H1
Antibodypedia	STK38L antibodies

PROTEIN BROWSER

STK38L-001	STK38L-004	STK38L-005	STK38L-006	STK38L-007	STK38L-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STK38L-001 ENSP00000373684 ENST00000389032	Q9Y2H1 [Direct mapping] Serine/threonine-protein kinase 38-like Show all	Enzymes ENZYME proteins Transferases Kinases AGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0003779 [actin binding] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] GO:0015629 [actin cytoskeleton] GO:0016020 [membrane] GO:0035556 [intracellular signal transduction] GO:0051128 [regulation of cellular component organization] Show all	464 aa 54 kDa	No	0
STK38L-004 ENSP00000437856 ENST00000541191	F5GY51 [Direct mapping] Serine/threonine-protein kinase 38-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	131 aa 15.3 kDa	No	0
STK38L-005 ENSP00000442253 ENST00000543246	F5GY51 [Direct mapping] Serine/threonine-protein kinase 38-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	131 aa 15.3 kDa	No	0
STK38L-006 ENSP00000440279 ENST00000544969	F5GY51 [Direct mapping] Serine/threonine-protein kinase 38-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	131 aa 15.3 kDa	No	0
STK38L-007 ENSP00000443838 ENST00000540996	F5H7Z3 [Direct mapping] Serine/threonine-protein kinase 38-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		94 aa 11.1 kDa	No	0
STK38L-012 ENSP00000439457 ENST00000545470	F5H277 [Direct mapping] Serine/threonine-protein kinase 38-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	214 aa 24.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.