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TAS2R50

GENERAL INFORMATION

Gene name

 TAS2R50

Gene description

 Taste receptor, type 2, member 50

Protein class

 G-protein coupled receptors
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Not detected

Protein evidence

 Evidence at transcript level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 TAS2R50 (HGNC Symbol)

Synonyms

 T2R51

Description

 Taste receptor, type 2, member 50 (HGNC Symbol)

Entrez gene summary

 TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). See also TAS2R10 (MIM 604791).[supplied by OMIM, Mar 2008]

Chromosome

 12

Cytoband

 p13.2

Chromosome location (bp)

 10985913 - 10986912

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000212126 (version 83.38)

Entrez gene

 259296

UniProt

 P59544 (UniProt - Evidence at transcript level)

neXtProt

 NX_P59544

Antibodypedia

 TAS2R50 antibodies

PROTEIN BROWSER
TAS2R50-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TAS2R50-001
ENSP00000424040
ENST00000506868
P59544 [Direct mapping]
Taste receptor type 2 member 50
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G-protein coupled receptors
   GPCRs excl olfactory receptors
   Family T2R receptors (taste receptor GPCRs)
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
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GO:0001580 [detection of chemical stimulus involved in sensory perception of bitter taste]
GO:0004930 [G-protein coupled receptor activity]
GO:0005886 [plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0016021 [integral component of membrane]
GO:0033038 [bitter taste receptor activity]
GO:0050909 [sensory perception of taste]
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 299 aa
34.6 kDa 		No 7

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.