Expression of C17orf51 in cancer - Summary - The Human Protein Atlas

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C17orf51

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C17orf51
Gene description	Chromosome 17 open reading frame 51
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enhanced (cerebral cortex)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA052106
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA052106

GENE INFORMATION
Gene name	C17orf51 (HGNC Symbol)
Synonyms	FLJ12977, FLJ31874, FLJ33618
Description	Chromosome 17 open reading frame 51 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p11.2
Chromosome location (bp)	21524790 - 21574458
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000212719 (version 83.38)
Entrez gene	339263
UniProt	A8MQB3 (UniProt - Evidence at transcript level)
neXtProt	NX_A8MQB3
Antibodypedia	C17orf51 antibodies

PROTEIN BROWSER

C17orf51-001	C17orf51-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C17orf51-001 ENSP00000384286 ENST00000391411	A8MQB3 [Direct mapping] Uncharacterized protein C17orf51 Show all	Predicted intracellular proteins Show all		221 aa 24.3 kDa	No	0
C17orf51-009 ENSP00000445158 ENST00000412778	H0YGX3 [Direct mapping] Uncharacterized protein C17orf51 Show all	Predicted intracellular proteins Show all		182 aa 19.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.