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HAUS7

GENERAL INFORMATION

Gene name

 HAUS7

Gene description

 HAUS augmin-like complex, subunit 7

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and cervical cancer (favourable).
Renal cancer p<0.001
Cervical cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 HAUS7 (HGNC Symbol)

Synonyms

 UCHL5IP, UIP1

Description

 HAUS augmin-like complex, subunit 7 (HGNC Symbol)

Entrez gene summary

 This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]

Chromosome

 X

Cytoband

 q28

Chromosome location (bp)

 153447666 - 153495516

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000213397 (version 83.38)

Entrez gene

 55559

UniProt

 Q99871 (UniProt - Evidence at protein level)

neXtProt

 NX_Q99871

Antibodypedia

 HAUS7 antibodies

PROTEIN BROWSER
HAUS7-002
HAUS7-007
HAUS7-010
HAUS7-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HAUS7-002
ENSP00000359230
ENST00000370211
Q99871 [Direct mapping]
HAUS augmin-like complex subunit 7
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0005874 [microtubule]
GO:0005886 [plasma membrane]
GO:0007067 [mitotic nuclear division]
GO:0031996 [thioesterase binding]
GO:0051225 [spindle assembly]
GO:0051297 [centrosome organization]
GO:0051301 [cell division]
GO:0070652 [HAUS complex]
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 368 aa
40.8 kDa 		No 0
HAUS7-007
ENSP00000359229
ENST00000370210
A6NDA1 [Direct mapping]
HAUS augmin-like complex subunit 7
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005886 [plasma membrane]
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 127 aa
14.2 kDa 		No 0
HAUS7-010
ENSP00000389431
ENST00000435662
H7BZF8 [Direct mapping]
HAUS augmin-like complex subunit 7
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   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 211 aa
23.1 kDa 		No 0
HAUS7-201
ENSP00000485783
ENST00000626181
A6NDA1 [Direct mapping]
HAUS augmin-like complex subunit 7
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005886 [plasma membrane]
Show all
 127 aa
14.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.