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MAGEA12
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Dictionary

GENERAL INFORMATION

Gene name

MAGEA12

Gene description

Melanoma antigen family A12

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Tissue enhanced (melanoma)
HPA (cell line):Cell line enhanced (HMC-1, K-562, PC-3, SH-SY5Y, U-2 OS, U-266/70)
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

Pending cancer tissue analysis.

PROGNOSTIC SUMMARY

Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Tissue enhanced (melanoma)

PROTEIN EXPRESSION

Pending cancer tissue analysis


STAINING SUMMARY

 

GENE INFORMATION

Gene name

MAGEA12 (HGNC Symbol)

Synonyms

CT1.12, MAGE12

Description

Melanoma antigen family A12 (HGNC Symbol)

Entrez gene summary

This gene is closely related to several other genes clustered on chromosome X. These genes may be overexpressed in tumors. Multiple alternatively spliced variants encoding the same protein have been identified. [provided by RefSeq, Jun 2014]

Chromosome

X

Cytoband

q28

Chromosome location (bp)

152733779 - 152737669

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000213401 (version 83.38)

Entrez gene

4111

UniProt

P43365 (UniProt - Evidence at transcript level)

neXtProt

NX_P43365

Antibodypedia

MAGEA12 antibodies

PROTEIN BROWSER

MAGEA12-001
MAGEA12-201
MAGEA12-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAGEA12-001
ENSP00000350592
ENST00000357916
P43365 [Direct mapping]
Melanoma-associated antigen 12
Q6FHH8 [Target identity:100%; Query identity:100%]
MAGEA12 protein; Melanoma antigen family A, 12; cDNA, FLJ94880, highly similar to Homo sapiens melanoma antigen, family A, 12 (MAGEA12), mRNA
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
Show all
314 aa
34.8 kDa
No 0
MAGEA12-201
ENSP00000377447
ENST00000393869
P43365 [Direct mapping]
Melanoma-associated antigen 12
Q6FHH8 [Target identity:100%; Query identity:100%]
MAGEA12 protein; Melanoma antigen family A, 12; cDNA, FLJ94880, highly similar to Homo sapiens melanoma antigen, family A, 12 (MAGEA12), mRNA
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
Show all
314 aa
34.8 kDa
No 0
MAGEA12-202
ENSP00000377478
ENST00000393900
P43365 [Direct mapping]
Melanoma-associated antigen 12
Q6FHH8 [Target identity:100%; Query identity:100%]
MAGEA12 protein; Melanoma antigen family A, 12; cDNA, FLJ94880, highly similar to Homo sapiens melanoma antigen, family A, 12 (MAGEA12), mRNA
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
Show all
314 aa
34.8 kDa
No 0

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