Expression of C8orf44 in cancer - Summary - The Human Protein Atlas

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C8orf44

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C8orf44
Gene description	Chromosome 8 open reading frame 44
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA043660
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), urothelial cancer (favourable) and pancreatic cancer (favourable).
Renal cancer p<0.001 Urothelial cancer p<0.001 Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043660

GENE INFORMATION
Gene name	C8orf44 (HGNC Symbol)
Synonyms	FLJ11267
Description	Chromosome 8 open reading frame 44 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q13.1
Chromosome location (bp)	66667615 - 66685564
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000213865 (version 83.38)
Entrez gene	56260
UniProt	Q96CB5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96CB5
Antibodypedia	C8orf44 antibodies

PROTEIN BROWSER

C8orf44-001	C8orf44-002	C8orf44-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C8orf44-001 ENSP00000375087 ENST00000390159	Q96CB5 [Direct mapping] Putative uncharacterized protein C8orf44 A0A024R7W3 [Target identity:100%; Query identity:100%] Chromosome 8 open reading frame 44, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005654 [nucleoplasm] Show all	159 aa 18.4 kDa	No	0
C8orf44-002 ENSP00000428002 ENST00000519561	Q96CB5 [Direct mapping] Putative uncharacterized protein C8orf44 A0A024R7W3 [Target identity:100%; Query identity:100%] Chromosome 8 open reading frame 44, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0005654 [nucleoplasm] Show all	159 aa 18.4 kDa	No	0
C8orf44-005 ENSP00000431104 ENST00000521889	E5RJQ3 [Direct mapping] Putative uncharacterized protein C8orf44 Show all	Predicted intracellular proteins Show all	GO:0005654 [nucleoplasm] Show all	85 aa 9.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.