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Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

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Score

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Antibodies

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LTB4R
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

LTB4R

Gene description

Leukotriene B4 receptor

Protein class

G-protein coupled receptors
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (skin)
GTEx:Expressed in all
FANTOM5:Tissue enhanced (lymph node, spleen)

Protein evidence

Evidence at protein level

Protein expression

Membranous and cytoplasmic expression in immune cells in several tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Antibody staining in cells/structures not annotated, view images.

Reliability score

Approved based on 1 antibody.
HPA003873
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
N/A
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (skin)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (lymph node, spleen)

GENE INFORMATION

Gene name

LTB4R (HGNC Symbol)

Synonyms

BLTR, CMKRL1, GPR16, LTB4R1, P2RY7, P2Y7

Description

Leukotriene B4 receptor (HGNC Symbol)

Entrez gene summary

Chromosome

14

Cytoband

q12

Chromosome location (bp)

24311450 - 24318036

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000213903 (version 83.38)

Entrez gene

1241

UniProt

Q15722 (UniProt - Evidence at protein level)

neXtProt

NX_Q15722

Antibodypedia

LTB4R antibodies

PROTEIN BROWSER

LTB4R-001
LTB4R-002
LTB4R-003
LTB4R-004
LTB4R-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LTB4R-001
ENSP00000307445
ENST00000345363
Q15722 [Direct mapping]
Leukotriene B4 receptor 1
Show all
Transporters
G-protein coupled receptors
   GPCRs excl olfactory receptors
   Adenosine and adenine nucleotide receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0001632 [leukotriene B4 receptor activity]
GO:0004930 [G-protein coupled receptor activity]
GO:0004974 [leukotriene receptor activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006928 [movement of cell or subcellular component]
GO:0006936 [muscle contraction]
GO:0006955 [immune response]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway]
GO:0007218 [neuropeptide signaling pathway]
GO:0008528 [G-protein coupled peptide receptor activity]
GO:0016021 [integral component of membrane]
GO:0061737 [leukotriene signaling pathway]
Show all
352 aa
37.6 kDa
No 7
LTB4R-002
ENSP00000380008
ENST00000396789
Q15722 [Direct mapping]
Leukotriene B4 receptor 1
Show all
Transporters
G-protein coupled receptors
   GPCRs excl olfactory receptors
   Adenosine and adenine nucleotide receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0001632 [leukotriene B4 receptor activity]
GO:0004930 [G-protein coupled receptor activity]
GO:0004974 [leukotriene receptor activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006928 [movement of cell or subcellular component]
GO:0006936 [muscle contraction]
GO:0006954 [inflammatory response]
GO:0006955 [immune response]
GO:0007165 [signal transduction]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway]
GO:0007218 [neuropeptide signaling pathway]
GO:0008528 [G-protein coupled peptide receptor activity]
GO:0016021 [integral component of membrane]
GO:0045121 [membrane raft]
GO:0061737 [leukotriene signaling pathway]
Show all
352 aa
37.6 kDa
No 7
LTB4R-003
ENSP00000380002
ENST00000396782
Q15722 [Direct mapping]
Leukotriene B4 receptor 1
Show all
Transporters
G-protein coupled receptors
   GPCRs excl olfactory receptors
   Adenosine and adenine nucleotide receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0001632 [leukotriene B4 receptor activity]
GO:0004930 [G-protein coupled receptor activity]
GO:0004974 [leukotriene receptor activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006928 [movement of cell or subcellular component]
GO:0006936 [muscle contraction]
GO:0006955 [immune response]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway]
GO:0007218 [neuropeptide signaling pathway]
GO:0008528 [G-protein coupled peptide receptor activity]
GO:0016021 [integral component of membrane]
GO:0061737 [leukotriene signaling pathway]
Show all
352 aa
37.6 kDa
No 7
LTB4R-004
ENSP00000450457
ENST00000553481
G3V244 [Direct mapping]
Leukotriene B4 receptor 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004930 [G-protein coupled receptor activity]
GO:0004974 [leukotriene receptor activity]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0016021 [integral component of membrane]
GO:0061737 [leukotriene signaling pathway]
Show all
102 aa
10.9 kDa
No 2
LTB4R-005
ENSP00000451929
ENST00000556141
G3V4Q5 [Direct mapping]
Leukotriene B4 receptor 1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004930 [G-protein coupled receptor activity]
GO:0004974 [leukotriene receptor activity]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0016021 [integral component of membrane]
GO:0061737 [leukotriene signaling pathway]
Show all
232 aa
24.9 kDa
No 3

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