Expression of TMEM213 in cancer - Summary - The Human Protein Atlas

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TMEM213

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM213
Gene description	Transmembrane protein 213
Protein class	Predicted membrane proteins Predicted secreted proteins
Predicted localization	Membrane,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (renal cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (kidney, salivary gland)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Expression in kidney and salivary gland.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA054059
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (renal cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA054059

GENE INFORMATION
Gene name	TMEM213
Synonyms
Description	Transmembrane protein 213 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q34
Chromosome location (bp)	138797952 - 138838101
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000214128 (version 83.38)
Entrez gene	155006
UniProt	A2RRL7 (UniProt - Inferred from homology)
neXtProt	NX_A2RRL7
Antibodypedia	TMEM213 antibodies

PROTEIN BROWSER

TMEM213-001	TMEM213-002	TMEM213-004	TMEM213-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM213-001 ENSP00000390407 ENST00000442682	A2RRL7 [Direct mapping] Transmembrane protein 213 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	107 aa 11.5 kDa	Yes	1
TMEM213-002 ENSP00000393891 ENST00000458494	A2RRL7 [Direct mapping] Transmembrane protein 213 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	83 aa 9.1 kDa	Yes	1
TMEM213-004 ENSP00000401570 ENST00000413208	A2RRL7 [Direct mapping] Transmembrane protein 213 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0016021 [integral component of membrane] Show all	105 aa 11.6 kDa	Yes	0
TMEM213-005 ENSP00000380727 ENST00000397602	A2RRL7 [Direct mapping] Transmembrane protein 213 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	106 aa 11.4 kDa	Yes	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.