Expression of C17orf67 in cancer - Summary - The Human Protein Atlas

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C17orf67

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C17orf67
Gene description	Chromosome 17 open reading frame 67
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (MOLT-4)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in intestinal tract and astrocytes in CNS.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA043479
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043479

GENE INFORMATION
Gene name	C17orf67
Synonyms
Description	Chromosome 17 open reading frame 67 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q22
Chromosome location (bp)	56791913 - 56838773
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000214226 (version 83.38)
Entrez gene	339210
UniProt	Q0P5P2 (UniProt - Evidence at protein level)
neXtProt	NX_Q0P5P2
Antibodypedia	C17orf67 antibodies

PROTEIN BROWSER

C17orf67-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C17orf67-001 ENSP00000380959 ENST00000397861	Q0P5P2 [Direct mapping] Uncharacterized protein C17orf67 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] Show all	90 aa 10.7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.