Cell atlas - MTCP1 - The Human Protein Atlas

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MTCP1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm
	Plasma membrane

Human cell
	Nucleoplasm
	Plasma Membrane

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GENERAL INFORMATION
Gene name	MTCP1
Gene description	Mature T-cell proliferation 1
Protein class	Cancer-related genes Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the plasma membrane.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Additional location	In addition localized to the Plasma membrane (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA032040
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the plasma membrane.

Main location

Nucleoplasm (approved)

Additional location

Plasma membrane (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA032040	HaCaT	Nucleoplasm
	HPA032040	HaCaT	Plasma membrane
	HPA032040	HeLa	Nucleus
	HPA032040	U-2 OS	Nucleoplasm
	HPA032040	U-2 OS	Plasma membrane

GENE INFORMATION
Gene name	MTCP1 (HGNC Symbol)
Synonyms	P13MTCP1, p8MTCP1
Description	Mature T-cell proliferation 1 (HGNC Symbol)
Entrez gene summary	This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the upstream 13 kDa protein that is a member of the TCL1 family. This protein may be involved in leukemogenesis. [provided by RefSeq, Mar 2009]
Chromosome	X
Cytoband	q28
Chromosome location (bp)	155061622 - 155147937
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000214827 (version 83.38)
Entrez gene	4515
UniProt	P56278 (UniProt - Evidence at protein level)
neXtProt	NX_P56278
Antibodypedia	MTCP1 antibodies

PROTEIN BROWSER

MTCP1-001	MTCP1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MTCP1-001 ENSP00000355058 ENST00000362018	P56278 [Direct mapping] Protein p13 MTCP-1 Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Show all	GO:0008283 [cell proliferation] Show all	107 aa 12.6 kDa	No	0
MTCP1-002 ENSP00000358488 ENST00000369476	P56278 [Direct mapping] Protein p13 MTCP-1 Show all	Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Protein evidence (Kim et al 2014) Show all	GO:0008283 [cell proliferation] Show all	107 aa 12.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.