Expression of GSG1L2 in cancer - Summary - The Human Protein Atlas

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GSG1L2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GSG1L2
Gene description	GSG1-like 2
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (renal cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (cerebral cortex, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA059428
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (renal cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA059428

GENE INFORMATION
Gene name	GSG1L2
Synonyms
Description	GSG1-like 2 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.1
Chromosome location (bp)	9802386 - 9822071
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000214978 (version 83.38)
Entrez gene	644070
UniProt	A8MUP6 (UniProt - Inferred from homology)
neXtProt	NX_A8MUP6
Antibodypedia	GSG1L2 antibodies

PROTEIN BROWSER

GSG1L2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GSG1L2-001 ENSP00000465978 ENST00000399363	A8MUP6 [Direct mapping] Germ cell-specific gene 1-like protein 2 K7EL98 [Direct mapping] Protein LOC644070 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	293 aa 32.4 kDa	Yes	3

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.