Tissue expression of GRID2IP - Summary - The Human Protein Atlas

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GRID2IP

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	GRID2IP
Gene description	Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Tissue enhanced (cerebellum)
FANTOM5:	Tissue enriched (cerebellum)

Protein evidence

Evidence at protein level

Protein expression

Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. External RNA data suggest low expression in cerebellum.
Reliability score	Uncertain based on 1 antibody. HPA045381
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

Cerebral cortex

Skeletal muscle

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebellum)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (cerebellum)

GENE INFORMATION
Gene name	GRID2IP
Synonyms
Description	Glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein (HGNC Symbol)
Entrez gene summary	Glutamate receptor delta-2 (GRID2; MIM 602368) is predominantly expressed at parallel fiber-Purkinje cell postsynapses and plays crucial roles in synaptogenesis and synaptic plasticity. GRID2IP1 interacts with GRID2 and may control GRID2 signaling in Purkinje cells (Matsuda et al., 2006 [PubMed 16835239]).[supplied by OMIM, Mar 2008]
Chromosome	7
Cytoband	p22.1
Chromosome location (bp)	6497462 - 6551436
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000215045 (version 83.38)
Entrez gene	392862
UniProt	A4D2P6 (UniProt - Inferred from homology)
neXtProt	NX_A4D2P6
Antibodypedia	GRID2IP antibodies

PROTEIN BROWSER

GRID2IP-001	GRID2IP-003	GRID2IP-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GRID2IP-001 ENSP00000397351 ENST00000457091	A4D2P6 [Direct mapping] Delphilin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0030054 [cell junction] GO:0043197 [dendritic spine] GO:0045202 [synapse] GO:0045211 [postsynaptic membrane] GO:0060292 [long term synaptic depression] Show all	1211 aa 132.3 kDa	No	0
GRID2IP-003 ENSP00000397887 ENST00000452113	C9J5F6 [Direct mapping] Delphilin Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	1020 aa 111.9 kDa	No	0
GRID2IP-004 ENSP00000408364 ENST00000435185	C9JNS8 [Direct mapping] Delphilin Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	1027 aa 112.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.