Expression of FAM166B in cancer - Summary

GENERAL INFORMATION
Gene name	FAM166B
Gene description	Family with sequence similarity 166, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (endometrial cancer, ovarian cancer)
HPA (cell line):	Cell line enhanced (Hep G2)
HPA (normal tissue):	Group enriched (adrenal gland, fallopian tube, skeletal muscle)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in respiratory epithelium, fallopian tube and skeletal muscle.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA045540
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PROGNOSTIC SUMMARY
Prognostic marker in ovarian cancer (favourable) and endometrial cancer (favourable).
Ovarian cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (endometrial cancer, ovarian cancer)

PROTEIN EXPRESSION

STAINING SUMMARY

HPA045540

GENE INFORMATION
Gene name	FAM166B
Synonyms
Description	Family with sequence similarity 166, member B (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p13.3
Chromosome location (bp)	35561831 - 35563899
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000215187 (version 83.38)
Entrez gene	730112
UniProt	A8MTA8 (UniProt - Evidence at transcript level)
neXtProt	NX_A8MTA8
Antibodypedia	FAM166B antibodies

PROTEIN BROWSER

FAM166B-005	FAM166B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM166B-005 ENSP00000382646 ENST00000399742	A8MTA8 [Direct mapping] Protein FAM166B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all		275 aa 30.6 kDa	No	0
FAM166B-201 ENSP00000480923 ENST00000619051	A0A087WXD4 [Direct mapping] Protein FAM166B Show all	Predicted intracellular proteins Show all		259 aa 29.2 kDa	No	0