Expression of RPTN in cancer - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	RPTN
Gene description	Repetin
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (head and neck cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (skin, tonsil)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Distinct cytoplasmic expression in a subset of keratinocytes in the inner root sheath of hair follicles and squamous epithelial tissue.

ANTIBODY IHC RELIABILITY
Data reliability description	External characterization data supports antibody staining.
Reliability score	Supported based on 2 antibodies. HPA030483 , HPA030485
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (head and neck cancer)

PROTEIN EXPRESSION

STAINING SUMMARY

HPA030483	HPA030485

GENE INFORMATION
Gene name	RPTN (HGNC Symbol)
Synonyms	FLJ39117
Description	Repetin (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	152153595 - 152159228
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000215853 (version 83.38)
Entrez gene	126638
UniProt	Q6XPR3 (UniProt - Evidence at protein level)
neXtProt	NX_Q6XPR3
Antibodypedia	RPTN antibodies

PROTEIN BROWSER

RPTN-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPTN-001 ENSP00000317895 ENST00000316073	Q6XPR3 [Direct mapping] Repetin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001533 [cornified envelope] GO:0005509 [calcium ion binding] GO:0005578 [proteinaceous extracellular matrix] Show all	784 aa 90.7 kDa	No	0