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Several cases of stomach cancer and rare cases of renal, urothelial, ovarian and lung cancer showed moderate to strong cytoplasmic and membranous positivity. Remaining cancers were weakly stained or negative.
Most cancer tissues showed weak to moderate cytoplasmic immunoreactivity, often seen with a granular pattern. Additional nucleolar positivity was observed in several cases. Non-Hodgkin's lymphomas were mainly negative.
Q8TF40 [Direct mapping] Folliculin-interacting protein 1
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SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001932 [regulation of protein phosphorylation] GO:0001934 [positive regulation of protein phosphorylation] GO:0002327 [immature B cell differentiation] GO:0002904 [positive regulation of B cell apoptotic process] GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0009267 [cellular response to starvation] GO:0031334 [positive regulation of protein complex assembly] GO:0031929 [TOR signaling] GO:0032007 [negative regulation of TOR signaling] GO:0033138 [positive regulation of peptidyl-serine phosphorylation] GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0043547 [positive regulation of GTPase activity] GO:2000973 [regulation of pro-B cell differentiation]
Q8TF40 [Direct mapping] Folliculin-interacting protein 1
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Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001932 [regulation of protein phosphorylation] GO:0001934 [positive regulation of protein phosphorylation] GO:0002327 [immature B cell differentiation] GO:0002904 [positive regulation of B cell apoptotic process] GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0009267 [cellular response to starvation] GO:0031334 [positive regulation of protein complex assembly] GO:0031929 [TOR signaling] GO:0032007 [negative regulation of TOR signaling] GO:0033138 [positive regulation of peptidyl-serine phosphorylation] GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0043547 [positive regulation of GTPase activity] GO:2000973 [regulation of pro-B cell differentiation]
Q8TF40 [Direct mapping] Folliculin-interacting protein 1
Show all
Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001932 [regulation of protein phosphorylation] GO:0001934 [positive regulation of protein phosphorylation] GO:0002327 [immature B cell differentiation] GO:0002904 [positive regulation of B cell apoptotic process] GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0009267 [cellular response to starvation] GO:0031334 [positive regulation of protein complex assembly] GO:0031929 [TOR signaling] GO:0032007 [negative regulation of TOR signaling] GO:0033138 [positive regulation of peptidyl-serine phosphorylation] GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0043547 [positive regulation of GTPase activity] GO:2000973 [regulation of pro-B cell differentiation]