Cell atlas - PAM16 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PAM16
Gene description	Presequence translocase-associated motor 16 homolog (S. cerevisiae)
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the mitochondria & nucleoplasm. In addition localized to the microtubules. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (uncertain), Mitochondria (supported)
Additional location	In addition localized to the Microtubules (uncertain)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA062721
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the mitochondria & nucleoplasm. In addition localized to the microtubules. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nucleoplasm (uncertain), Mitochondria (supported)

Additional location

Microtubules (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA062721	CACO-2	Nucleoplasm
HPA062721	CACO-2	Mitochondria
HPA062721	MCF7	Nucleoplasm
		Microtubules
		Mitochondria
HPA062721	U-2 OS	Nucleoplasm
		Microtubules
		Mitochondria

GENE INFORMATION
Gene name	PAM16 (HGNC Symbol)
Synonyms	Magmas, Tim16, TIMM16
Description	Presequence translocase-associated motor 16 homolog (S. cerevisiae) (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	4331549 - 4355607
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000217930 (version 83.38)
Entrez gene	51025
UniProt	Q9Y3D7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y3D7
Antibodypedia	PAM16 antibodies

PROTEIN BROWSER

PAM16-001	PAM16-002	PAM16-005	PAM16-012	PAM16-014	PAM16-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PAM16-001 ENSP00000315693 ENST00000318059	Q9Y3D7 [Direct mapping] Mitochondrial import inner membrane translocase subunit TIM16 Show all	SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Disease related genes Show all	GO:0001405 [presequence translocase-associated import motor] GO:0001503 [ossification] GO:0005515 [protein binding] GO:0005744 [mitochondrial inner membrane presequence translocase complex] GO:0005759 [mitochondrial matrix] GO:0006626 [protein targeting to mitochondrion] GO:0030150 [protein import into mitochondrial matrix] GO:0031314 [extrinsic component of mitochondrial inner membrane] GO:0032780 [negative regulation of ATPase activity] GO:0043234 [protein complex] GO:0044267 [cellular protein metabolic process] Show all	125 aa 13.8 kDa	No	0
PAM16-002 ENSP00000461047 ENST00000576217	Q9Y3D7 [Direct mapping] Mitochondrial import inner membrane translocase subunit TIM16 Show all	SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Disease related genes Show all	GO:0001405 [presequence translocase-associated import motor] GO:0001503 [ossification] GO:0005515 [protein binding] GO:0005744 [mitochondrial inner membrane presequence translocase complex] GO:0005759 [mitochondrial matrix] GO:0006626 [protein targeting to mitochondrion] GO:0030150 [protein import into mitochondrial matrix] GO:0031314 [extrinsic component of mitochondrial inner membrane] GO:0032780 [negative regulation of ATPase activity] GO:0043234 [protein complex] GO:0044267 [cellular protein metabolic process] Show all	125 aa 13.8 kDa	No	0
PAM16-005 ENSP00000459113 ENST00000577031	I3L1U7 [Direct mapping] Mitochondrial import inner membrane translocase subunit TIM16 Show all	SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Show all	GO:0005744 [mitochondrial inner membrane presequence translocase complex] Show all	129 aa 14 kDa	No	0
PAM16-012 ENSP00000460708 ENST00000571941	I3L3T0 [Direct mapping] HCG15164, isoform CRA_b; Mitochondrial import inner membrane translocase subunit TIM16 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0005744 [mitochondrial inner membrane presequence translocase complex] GO:0030150 [protein import into mitochondrial matrix] Show all	145 aa 15.9 kDa	No	0
PAM16-014 ENSP00000458412 ENST00000575848	I3L0X9 [Direct mapping] Mitochondrial import inner membrane translocase subunit TIM16 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005744 [mitochondrial inner membrane presequence translocase complex] Show all	137 aa 15.1 kDa	No	0
PAM16-015 ENSP00000459955 ENST00000573553	I3L3T0 [Direct mapping] HCG15164, isoform CRA_b; Mitochondrial import inner membrane translocase subunit TIM16 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0005744 [mitochondrial inner membrane presequence translocase complex] GO:0030150 [protein import into mitochondrial matrix] Show all	145 aa 15.9 kDa	No	0