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PPP1R3G

GENERAL INFORMATION

Gene name

 PPP1R3G

Gene description

 Protein phosphatase 1, regulatory subunit 3G

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enhanced (liver cancer)
HPA (cell line):Cell line enhanced (EFO-21, PC-3, THP-1)
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA056393
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enhanced (liver cancer)
0.01020304050607080FPKMBreast cancer (BRCA)Cervical cancer (CESC)Colorectal cancer (COAD,READ)Endometrial cancer (UCEC)Glioma (GBM)Head and neck cancer (HNSC)Liver cancer (LIHC)Lung cancer (LUAD,LUSC)Melanoma (SKCM)Ovarian cancer (OV)Pancreatic cancer (PAAD)Prostate cancer (PRAD)Renal cancer (KICH,KIRC,KIRP)Stomach cancer (STAD)Testis cancer (TGCT)Thyroid cancer (THCA)Urothelial cancer (BLCA)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA056393

Cancer

Cancer staining
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Cancer

Cancer staining
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

 Rare case of duct carcinoma of breast cancer displayed strong cytoplasmic staining. Remaining cancer tissues were negative.

GENE INFORMATION

Gene name

 PPP1R3G

Synonyms

Description

 Protein phosphatase 1, regulatory subunit 3G (HGNC Symbol)

Entrez gene summary

Chromosome

 6

Cytoband

 p25.1

Chromosome location (bp)

 5084581 - 5089487

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000219607 (version 83.38)

Entrez gene

 648791

UniProt

 B7ZBB8 (UniProt - Evidence at protein level)

neXtProt

 NX_B7ZBB8

Antibodypedia

 PPP1R3G antibodies

PROTEIN BROWSER
PPP1R3G-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PPP1R3G-001
ENSP00000393832
ENST00000405617
B7ZBB8 [Direct mapping]
Protein phosphatase 1 regulatory subunit 3G
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0019903 [protein phosphatase binding]
GO:0042593 [glucose homeostasis]
GO:0045725 [positive regulation of glycogen biosynthetic process]
GO:2000467 [positive regulation of glycogen (starch) synthase activity]
GO:2001069 [glycogen binding]
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 358 aa
38 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.