Expression of FAM228B in cancer - Summary - The Human Protein Atlas

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FAM228B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM228B
Gene description	Family with sequence similarity 228, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA052598
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA052598

GENE INFORMATION
Gene name	FAM228B
Synonyms
Description	Family with sequence similarity 228, member B (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p23.3
Chromosome location (bp)	24076526 - 24169640
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000219626 (version 83.38)
Entrez gene	375190
UniProt
neXtProt
Antibodypedia	FAM228B antibodies

PROTEIN BROWSER

FAM228B-003	FAM228B-007	FAM228B-009	FAM228B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM228B-003 ENSP00000479742 ENST00000613899	A0A087WVX1 [Direct mapping] HCG1820835, isoform CRA_b; Protein FAM228B Show all	Predicted intracellular proteins Show all		187 aa 21.9 kDa	No	0
FAM228B-007 ENSP00000482482 ENST00000615575	A0A087WZA1 [Direct mapping] HCG1820835, isoform CRA_a; Protein FAM228B Show all	Predicted intracellular proteins Show all		324 aa 38.1 kDa	No	0
FAM228B-009 ENSP00000482790 ENST00000611138	A0A087WZN6 [Direct mapping] Protein FAM228B Show all	Predicted intracellular proteins Show all		38 aa 4.3 kDa	No	0
FAM228B-201 ENSP00000483011 ENST00000611127	A0A087WZA1 [Direct mapping] HCG1820835, isoform CRA_a; Protein FAM228B Show all	Predicted intracellular proteins Show all		324 aa 38.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.