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A few cases of melanoma, prostate, urothelial and pancreatic cancer showed moderate nuclear positivity. Moderate cytoplasmic and membranous staining was observed in a few renal cancers. Other cancer tissues were negative.
GENE INFORMATION
Gene name
ZNF816-ZNF321P (HGNC Symbol)
Synonyms
ZNF816-ZNF321
Description
ZNF816-ZNF321P readthrough (HGNC Symbol)
Entrez gene summary
This locus represents naturally occurring read-through transcription between the zinc finger protein 816 (ZNF816) gene and the zinc finger protein 321 (ZNF321) pseudogene on chromosome 19. The read-through transcript encodes a KRAB domain-containing protein that shares sequence identity with the upstream gene product, but it contains a distinct C-terminus encoded by exon structure from the downstream pseudogene. [provided by RefSeq, Jan 2011]