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RAB6C

GENERAL INFORMATION

Gene name

 RAB6C

Gene description

 RAB6C, member RAS oncogene family

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enhanced (prostate cancer)
HPA (cell line):Cell line enhanced (BEWO, HMC-1, REH, T-47d)
HPA (normal tissue):Tissue enhanced (parathyroid gland)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene.

Reliability score

 Uncertain based on 1 antibody.
HPA059131
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enhanced (prostate cancer)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA059131

GENE INFORMATION

Gene name

 RAB6C (HGNC Symbol)

Synonyms

 WTH3

Description

 RAB6C, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q21.1

Chromosome location (bp)

 129979664 - 129982738

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000222014 (version 83.38)

Entrez gene

 84084

UniProt

 Q9H0N0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H0N0

Antibodypedia

 RAB6C antibodies

PROTEIN BROWSER
RAB6C-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAB6C-001
ENSP00000387307
ENST00000410061
Q9H0N0 [Direct mapping]
Ras-related protein Rab-6C
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Predicted intracellular proteins
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GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005794 [Golgi apparatus]
GO:0005813 [centrosome]
GO:0006886 [intracellular protein transport]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006891 [intra-Golgi vesicle-mediated transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0010824 [regulation of centrosome duplication]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0022402 [cell cycle process]
GO:0032482 [Rab protein signal transduction]
GO:0042147 [retrograde transport, endosome to Golgi]
GO:0042493 [response to drug]
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 254 aa
28.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.