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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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CROCC2
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

CROCC2

Gene description

Ciliary rootlet coiled-coil, rootletin family member 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Tissue enhanced (endometrial cancer)
HPA (cell line):Cell line enhanced (RPMI-8226)
HPA (normal tissue):Group enriched (fallopian tube, spleen)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

Uncertain based on 1 antibody.
HPA048678
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Tissue enhanced (endometrial cancer)

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA048678

Cancer

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Cancer

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary

Most malignant cells displayed weak to moderate nuclear positivity. Additional cytoplasmic staining was observed in several malignant melanomas. Many malignant lymphomas were negative.

GENE INFORMATION

Gene name

CROCC2

Synonyms

Description

Ciliary rootlet coiled-coil, rootletin family member 2 (HGNC Symbol)

Entrez gene summary

Chromosome

2

Cytoband

q37.3

Chromosome location (bp)

240906330 - 240993311

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000226321 (version 83.38)

Entrez gene

UniProt

H7BZ55 (UniProt - Uncertain)

neXtProt

NX_H7BZ55

Antibodypedia

CROCC2 antibodies

PROTEIN BROWSER

CROCC2-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CROCC2-006
ENSP00000397968
ENST00000443866
H7BZ55 [Target identity:100%; Query identity:100%]
Putative ciliary rootlet coiled-coil protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
1655 aa
185.9 kDa
No 0

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