Expression of CROCC2 in cancer - Summary - The Human Protein Atlas

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CROCC2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CROCC2
Gene description	Ciliary rootlet coiled-coil, rootletin family member 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (endometrial cancer)
HPA (cell line):	Cell line enhanced (RPMI-8226)
HPA (normal tissue):	Group enriched (fallopian tube, spleen)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA048678
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (endometrial cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA048678

GENE INFORMATION
Gene name	CROCC2
Synonyms
Description	Ciliary rootlet coiled-coil, rootletin family member 2 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q37.3
Chromosome location (bp)	240906330 - 240993311
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000226321 (version 83.38)
Entrez gene
UniProt	H7BZ55 (UniProt - Uncertain)
neXtProt	NX_H7BZ55
Antibodypedia	CROCC2 antibodies

PROTEIN BROWSER

CROCC2-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CROCC2-006 ENSP00000397968 ENST00000443866	H7BZ55 [Target identity:100%; Query identity:100%] Putative ciliary rootlet coiled-coil protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		1655 aa 185.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.