Expression of CT45A5 in cancer - Summary - The Human Protein Atlas

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CT45A5

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CT45A5
Gene description	Cancer/testis antigen family 45, member A5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enhanced (HMC-1, Karpas-707, U-266/84)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective nuclear expression in cells of seminiferous ducts in testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Caution, targets protein from more than one gene.
Reliability score	Supported based on 4 antibodies. HPA044735 , HPA044757 , HPA046872 , HPA046987
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044735	HPA044757	HPA046872	HPA046987

GENE INFORMATION
Gene name	CT45A5 (HGNC Symbol)
Synonyms	CT45-5, CT45.5
Description	Cancer/testis antigen family 45, member A5 (HGNC Symbol)
Entrez gene summary	This gene represents one of a cluster of several similar genes located on the q arm of chromosome X. The genes in this cluster encode members of the cancer/testis (CT) family of antigens, and are distinct from other CT antigens. These antigens are thought to be novel therapeutic targets for human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Chromosome	X
Cytoband	q26.3
Chromosome location (bp)	135777130 - 135785298
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000228836 (version 83.38)
Entrez gene	441521
UniProt	P0DMU8 (UniProt - Evidence at transcript level)
neXtProt	NX_P0DMU8
Antibodypedia	CT45A5 antibodies

PROTEIN BROWSER

CT45A5-001	CT45A5-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CT45A5-001 ENSP00000427342 ENST00000487941	P0DMU8 [Direct mapping] Cancer/testis antigen family 45 member A5 Show all	Predicted intracellular proteins Show all		189 aa 21.2 kDa	No	0
CT45A5-201 ENSP00000483658 ENST00000617203	P0DMU8 [Direct mapping] Cancer/testis antigen family 45 member A5 Show all	Predicted intracellular proteins Show all		189 aa 21.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.