Expression of PHGR1 in cancer - Summary - The Human Protein Atlas

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PHGR1

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PHGR1
Gene description	Proline/histidine/glycine-rich 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (colorectal cancer, stomach cancer)
HPA (cell line):	Cell line enhanced (BEWO, HaCaT, SCLC-21H)
HPA (normal tissue):	Group enriched (colon, duodenum, rectum, small intestine)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Distinct cytoplasmic and nuclear expression in gastrointestinal mucosa.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA068787
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PROGNOSTIC SUMMARY
Prognostic marker in breast cancer (favourable).
Breast cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (colorectal cancer, stomach cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA068787

GENE INFORMATION
Gene name	PHGR1
Synonyms
Description	Proline/histidine/glycine-rich 1 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q15.1
Chromosome location (bp)	40351033 - 40356434
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000233041 (version 83.38)
Entrez gene	644844
UniProt	C9JFL3 (UniProt - Predicted)
neXtProt	NX_C9JFL3
Antibodypedia	PHGR1 antibodies

PROTEIN BROWSER

PHGR1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PHGR1-001 ENSP00000410024 ENST00000448599	C9JFL3 [Direct mapping] Proline, histidine and glycine-rich protein 1 Show all	Predicted intracellular proteins Show all		82 aa 7.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.