Expression of CTXN2 in cancer - Summary - The Human Protein Atlas

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CTXN2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CTXN2
Gene description	Cortexin 2
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (cerebral cortex, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Extracellular deposits and cytoplasmic expression in several different tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA053168
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA053168

GENE INFORMATION
Gene name	CTXN2
Synonyms
Description	Cortexin 2 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q21.1
Chromosome location (bp)	48191539 - 48203756
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000233932 (version 83.38)
Entrez gene	399697
UniProt	P0C2S0 (UniProt - Inferred from homology)
neXtProt	NX_P0C2S0
Antibodypedia	CTXN2 antibodies

PROTEIN BROWSER

CTXN2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CTXN2-001 ENSP00000406145 ENST00000417307	P0C2S0 [Direct mapping] Cortexin-2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] GO:0031224 [intrinsic component of membrane] Show all	81 aa 9 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.