Expression of HGH1 in cancer - Summary - The Human Protein Atlas

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HGH1

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	HGH1
Gene description	HGH1 homolog
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (PC-3)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and/or nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA042470
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and cervical cancer (unfavourable).
Renal cancer p<0.001 Cervical cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042470

GENE INFORMATION
Gene name	HGH1 (HGNC Symbol)
Synonyms	C8orf30A, C8orf30B, FAM203A, FAM203B, FLJ40907, LOC51236
Description	HGH1 homolog (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q24.3
Chromosome location (bp)	144137769 - 144140843
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000235173 (version 83.38)
Entrez gene	51236
UniProt	Q9BTY7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BTY7
Antibodypedia	HGH1 antibodies

PROTEIN BROWSER

HGH1-001	HGH1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HGH1-001 ENSP00000321320 ENST00000347708	Q9BTY7 [Direct mapping] Protein HGH1 homolog Show all	Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005488 [binding] GO:0005575 [cellular_component] GO:0008150 [biological_process] Show all	390 aa 42.1 kDa	No	0
HGH1-201 ENSP00000486087 ENST00000628266	E9PIX0 [Direct mapping] Protein HGH1 homolog Show all	Predicted intracellular proteins Show all		85 aa 8.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.