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Many cases of colorectal, ovarian, stomach, pancreatic and liver cancers displayed moderate to strong positivity. Remaining malignant tissues were negative or weakly stained.
GENE INFORMATION
Gene name
NFAM1 (HGNC Symbol)
Synonyms
CNAIP
Description
NFAT activating protein with ITAM motif 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters. The encoded protein contains an immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells. [provided by RefSeq, Jul 2008]