Expression of FAM200B in cancer - Summary - The Human Protein Atlas

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FAM200B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM200B
Gene description	Family with sequence similarity 200, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA017855
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable), renal cancer (favourable), pancreatic cancer (favourable) and lung cancer (favourable).
Urothelial cancer p<0.001 Renal cancer p<0.001 Pancreatic cancer p<0.001 Lung cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA017855

GENE INFORMATION
Gene name	FAM200B (HGNC Symbol)
Synonyms	C4orf53
Description	Family with sequence similarity 200, member B (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	p15.32
Chromosome location (bp)	15681662 - 15705565
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000237765 (version 83.38)
Entrez gene	285550
UniProt	P0CF97 (UniProt - Inferred from homology)
neXtProt	NX_P0CF97
Antibodypedia	FAM200B antibodies

PROTEIN BROWSER

FAM200B-005	FAM200B-011	FAM200B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM200B-005 ENSP00000393017 ENST00000422728	P0CF97 [Direct mapping] Protein FAM200B Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] Show all	657 aa 76 kDa	No	0
FAM200B-011 ENSP00000422751 ENST00000503617	D6RAC6 [Direct mapping] Protein FAM200B Show all	Predicted intracellular proteins Show all		24 aa 2.9 kDa	No	0
FAM200B-201 ENSP00000483930 ENST00000622362	P0CF97 [Direct mapping] Protein FAM200B Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	657 aa 76 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.