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MRPL33

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GENERAL INFORMATION

Gene name

 MRPL33

Gene description

 Mitochondrial ribosomal protein L33

Protein class

 Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 MRPL33 (HGNC Symbol)

Synonyms

 C2orf1, RPL33L

Description

 Mitochondrial ribosomal protein L33 (HGNC Symbol)

Entrez gene summary

 Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 p23.2

Chromosome location (bp)

 27771717 - 27988087

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000243147 (version 83.38)

Entrez gene

 9553

UniProt

 O75394 (UniProt - Evidence at protein level)

neXtProt

 NX_O75394

Antibodypedia

 MRPL33 antibodies

PROTEIN BROWSER
MRPL33-001
MRPL33-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MRPL33-001
ENSP00000296102
ENST00000296102
O75394 [Direct mapping]
39S ribosomal protein L33, mitochondrial
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005762 [mitochondrial large ribosomal subunit]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006996 [organelle organization]
GO:0032543 [mitochondrial translation]
GO:0070124 [mitochondrial translational initiation]
GO:0070125 [mitochondrial translational elongation]
GO:0070126 [mitochondrial translational termination]
Show all
 65 aa
7.6 kDa 		No 0
MRPL33-002
ENSP00000368988
ENST00000379666
O75394 [Direct mapping]
39S ribosomal protein L33, mitochondrial
Show all
Ribosomal proteins
   Phobius predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005743 [mitochondrial inner membrane]
GO:0005762 [mitochondrial large ribosomal subunit]
GO:0006996 [organelle organization]
GO:0032543 [mitochondrial translation]
GO:0070124 [mitochondrial translational initiation]
GO:0070125 [mitochondrial translational elongation]
GO:0070126 [mitochondrial translational termination]
Show all
 54 aa
6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.