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A majority of cases in testicular seminomas, colorectal, endometrial, renal and urothelial cancers were moderately stained. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
PGBD3 (HGNC Symbol)
Synonyms
FLJ90201
Description
PiggyBac transposable element derived 3 (HGNC Symbol)
Entrez gene summary
This gene is a member of a small family of genes derived from piggyBac transposable elements. The encoded protein contains a zinc-ribbon domain characteristic of transposon-derived proteins and may function as a regulator of transcription. Naturally-occurring readthrough transcription occurs between this gene and the adjacent ERCC6 gene (GeneID 2074), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544. There are several pseudogenes for this gene on chromosomes 4, 5 and 12. [provided by RefSeq, Mar 2013]