Expression of RBM14-RBM4 in cancer - Summary - The Human Protein Atlas

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RBM14-RBM4

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RBM14-RBM4
Gene description	RBM14-RBM4 readthrough
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Not detected

Protein evidence

Evidence at protein level

Protein expression
normal tissue

RNA-based expert annotation gave inconclusive results.

ANTIBODY IHC RELIABILITY
Data reliability description	No RNA expression data detected and pending external verification. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 1 antibody. HPA047849
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA047849

GENE INFORMATION
Gene name	RBM14-RBM4
Synonyms
Description	RBM14-RBM4 readthrough (HGNC Symbol)
Entrez gene summary	This locus represents naturally occurring read-through transcription between the neighboring RBM14 (RNA binding motif protein 14) and RBM4 (RNA binding motif protein 4) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with each individual gene product. This fusion protein contains RRM and zinc finger domains, and it functions to stimulate transcription in a hormone and receptor-dependent manner. [provided by RefSeq, Nov 2010]
Chromosome	11
Cytoband	q13.2
Chromosome location (bp)	66616626 - 66646469
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000248643 (version 83.38)
Entrez gene	100526737
UniProt
neXtProt
Antibodypedia	RBM14-RBM4 antibodies

PROTEIN BROWSER

RBM14-RBM4-002	RBM14-RBM4-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBM14-RBM4-002 ENSP00000421279 ENST00000500635	A0A0A6YYI9 [Direct mapping] Protein RBM14-RBM4 Show all	Predicted intracellular proteins Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	118 aa 12.9 kDa	No	0
RBM14-RBM4-004 ENSP00000388552 ENST00000412278		Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0008270 [zinc ion binding] Show all	339 aa 37 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.