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EPPIN-WFDC6

GENERAL INFORMATION

Gene name

 EPPIN-WFDC6

Gene description

 EPPIN-WFDC6 readthrough

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Group enriched (epididymis, testis)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 EPPIN-WFDC6 (HGNC Symbol)

Synonyms

 SPINLW1-WFDC6

Description

 EPPIN-WFDC6 readthrough (HGNC Symbol)

Entrez gene summary

 This locus represents naturally occurring read-through transcription between the neighboring SPINLW1 (serine peptidase inhibitor-like, with Kunitz and WAP domains 1) and WFDC6 (WAP four-disulfide core domain 6) genes. The read-through transcript encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010]

Chromosome

 20

Cytoband

 q13.12

Chromosome location (bp)

 45536986 - 45547426

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000249139 (version 83.38)

Entrez gene

 100526773

UniProt

 O95925 (UniProt - Evidence at protein level)

neXtProt

 NX_O95925

Antibodypedia

 EPPIN-WFDC6 antibodies

PROTEIN BROWSER
EPPIN-WFDC6-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
EPPIN-WFDC6-001
ENSP00000424176
ENST00000504988
O95925 [Direct mapping]
Eppin
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   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
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GO:0004867 [serine-type endopeptidase inhibitor activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0009986 [cell surface]
GO:0010466 [negative regulation of peptidase activity]
GO:0010951 [negative regulation of endopeptidase activity]
GO:0030414 [peptidase inhibitor activity]
GO:0042742 [defense response to bacterium]
GO:0043234 [protein complex]
GO:0051259 [protein oligomerization]
GO:0090281 [negative regulation of calcium ion import]
GO:1901318 [negative regulation of sperm motility]
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 179 aa
20.5 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.